Compounding topical medications can help tailor the treatment of wounds to individual patient needs and may offer wound healing effects that are not otherwise available. This author explores how compounded topical medication can reduce pain, stimulate new tissue healing, increase vascular perfusion and decrease bioburden.
The advantage of compounding medications in the treatment of wounds is that the treatment is site directed, and not dependent on systemic circulation. Therefore, in the presence of decreased vascular perfusion, topically applied medications may achieve therapeutic benefits that would not otherwise occur if one administered the same medication systemically. Examples might include medications such as pentoxifylline (Trental, Sanofi Aventis).
In addition, adherence is easier when one topical medication is required for the treatment of the wound rather than the application of multiple preparations. Such an example would include patients who require collagenase for debridement and perhaps a topical antiseptic or antibiotic. With topical compounded therapy, one can combine these medications into one cream or ointment, which also offers the potential for reduced wound care costs.